Dr Jay Siak

Dr. Jay Siak is a Senior Consultant Ophthalmologist at Eagle Eye Centre in Singapore. He is also a Visiting Consultant attending physician in the Ocular Inflammation and Immunology department at the Singapore National Eye Centre (SNEC). He graduated from the National University of Singapore in 2004, where he was awarded the Dean’s list award for academic excellence.

He received the Ministry of Health Post-graduate Training Scholarship in 2012 for specialist training and Healthcare Research Scholarship for Master of Clinical Investigation in 2013. He completed his ophthalmology residency at SNEC and received his Master of Medicine (Ophth) in 2012, Master of Clinical Investigation in 2015 and became a fellow of the Royal College of Ophthalmologists (London), Academy of Medicine (Singapore) in 2015, and Royal College of Surgeons (Edinburgh) in 2016. He completed his clinical fellowship in Ocular Inflammation and Immunology at SNEC in 2016, followed by a two years ocular immunology fellowship (2017-2019) under James Rosenbaum (MD) at Casey Eye Institute, Oregon, and Rachel Caspi (PhD) at National Eye Institute, National Institutes of Health, Maryland, USA. He was an attending physician at SNEC from 2019 to 2023 and a Clinical Assistant Professor with the Duke-NUS Medical School prior to joining another private practice group My Eye Specialist & Retina Surgeon Clinic from 1st April 2023 to 31st March 2025.

He received a Singapore National Medical Research Council new investigator grant in 2014 to study viral inflammatory glaucoma such as infective viral uveitis. These conditions were associated with recurrent intraocular cytomegalovirus (CMV) reactivation which resulted in glaucomatous visual loss among younger individuals.

He received further immunology training from Dr. Rachel Caspi (PhD) at the Laboratory of Immunology at NIH where his research focused on aberrant interactions between the commensal microbiome and ocular surface immunity in patients with autoinflammatory disease. His other research interests included the epidemiology of uveitic conditions, and diagnostic modalities and treatment for uveitis. He was involved in the teaching of medical students from Duke-NUS Medical School and NUS Yong Loo Lin School of Medicine, and the training of residents and clinical fellows at SNEC.